FC LAB (Chow Lab) We are part of the HTI Microbe Lab!
PUBLICATIONS
Molecular Biology and Microbiology
1: Kwok CT, Wong CC, Li JJ, Kwan YW, Leung GP, Tsoi B, Chow FW, Seto SW.Lipopolysaccharide (LPS) induces sclerostin secretion by extracellular vesiclevia TLR4/miR-92a-3p/PTEN/NF-κB signalling pathway in murine macrophage. InflammRes. 2025 Jan 25;74(1):27. doi: 10.1007/s00011-024-01987-1. PMID: 39862242.
2: Wong YN, Hau PT, Chau EC, Ng LC, Murillo M, Fung J, Po WW, Yu RC, Kam MK, TamEW, Tsang CC, Chow FW. Enhanced Specificity in Colorimetric LAMP Assay for Sarocladium kiliense Detection Using a Combination of Two Additives. JFungi (Basel). 2024 Dec 11;10(12):857. doi: 10.3390/jof10120857. PMID: 39728353;PMCID: PMC11678401.
3: Blow F, Jeffrey K, Chow FW, Nikonorova IA, Barr MM, Cook AG, Prevo B,Cheerambathur DK, Buck AH. SID-2 is a conserved extracellular vesicle proteinthat is not associated with environmental RNAi in parasitic nematodes. OpenBiol. 2024 Nov;14(11):240190. doi: 10.1098/rsob.240190. Epub 2024 Nov 6. PMID:39501794; PMCID: PMC11538922.
4: Kwok CT, Yu RC, Hau PT, Cheung KY, Ng IC, Fung J, Wong IT, Yau MC, Liu WM,Kong HK, Siu GK, Chow FW, Seto SW. Characteristics and pathogenicity of<i>Vibrio alginolyticus</i> SWS causing high mortality in mud crab (Scyllaserrata) aquaculture in Hong Kong. Front Cell Infect Microbiol. 2024 Jul23;14:1425104. doi: 10.3389/fcimb.2024.1425104. PMID: 39108984; PMCID:PMC11300173.
5: Wang M, Jin L, Hang-Mei Leung P, Wang-Ngai Chow F, Zhao X, Chen H, Pan W, LiuH, Li S. Advancements in magnetic nanoparticle-based biosensors for point-of-care testing. Front Bioeng Biotechnol. 2024 Apr 25;12:1393789. doi:10.3389/fbioe.2024.1393789. PMID: 38725992; PMCID: PMC11079239.
6: Lee AW, Ng IC, Wong EY, Wong IT, Sze RP, Chan KY, So TY, Zhang Z, Ka-Yee FungS, Choi-Ying Wong S, Tam WY, Lao HY, Lee LK, Leung JS, Chan CT, Ng TT, Zhang J,Chow FW, Leung PH, Siu GK. Comprehensive identification of pathogenic microbesand antimicrobial resistance genes in food products using nanopore sequencing-based metagenomics. Food Microbiol. 2024 Aug;121:104493. doi:10.1016/j.fm.2024.104493. Epub 2024 Mar 18. PMID: 38637066.
7: Lao HY, Wong LL, Hui Y, Ng TT, Chan CT, Lo HW, Yau MC, Leung EC, Wong RC, HoAY, Yip KT, Lam JY, Chow VC, Luk KS, Que TL, Chow FWN, Siu GK. The clinicalutility of Nanopore 16S rRNA gene sequencing for direct bacterial identificationin normally sterile body fluids. Front Microbiol. 2024 Jan 9;14:1324494. doi:10.3389/fmicb.2023.1324494. PMID: 38264489; PMCID: PMC10803466.
8: Chan TT-Y, Chow FW-N, Fung J, Cheng FK-K, Lo GC-S, Tsang C-C, Luk HK-H, WongAC-P, He Z, Aw-Yong KL, Liu X, Yuen K-Y, Woo PC-Y, Lau SK-P. A sensitive andsimple RT-LAMP assay for sarbecovirus screening in bats. Microbiol Spectr. 2023Dec 12;11(6):e0259123. doi: 10.1128/spectrum.02591-23. Epub 2023 Nov 16. PMID:37971222; PMCID: PMC10715088.
9: Ayesha A, Chow FW, Leung PH. Role of Legionella pneumophila outermembrane vesicles in host-pathogen interaction. Front Microbiol. 2023 Sep25;14:1270123. doi: 10.3389/fmicb.2023.1270123. PMID: 37817751; PMCID:PMC10561282.
10: Chan W, Chow FW, Tsang CC, Liu X, Yao W, Chan TT, Siu GK, Ho AY, Luk KS, LauSK, Woo PC. Induction of amphotericin B resistance in susceptible Candida auris by extracellular vesicles. Emerg Microbes Infect. 2022Dec;11(1):1900-1909. doi: 10.1080/22221751.2022.2098058. PMID: 35786393; PMCID:PMC9341352.
11: Yang J, Liu H, Pan W, Song M, Lu Y, Wang-Ngai Chow F, Hang-Mei Leung P, DengY, Hori M, He N, Li S. Recent Advances of Human Leukocyte Antigen (HLA) TypingTechnology Based on High-Throughput Sequencing. J Biomed Nanotechnol. 2022 Mar1;18(3):617-639. doi: 10.1166/jbn.2022.3280. PMID: 35715925.
12: Chen Z, Zhao K, Tan B, Tong Z, He Z, Luo X, Cai L, Wang H, Leung PHM, ChowFW, Chen H, Deng Y. Development of a high specificity typing method for thedetection of herpes simplex virus. Front Bioeng Biotechnol. 2022 Aug17;10:955713. doi: 10.3389/fbioe.2022.955713. PMID: 36061450; PMCID: PMC9428506.
13: Chow FW. Genomics: Infectious Disease and Host-Pathogen Interaction. Int JMol Sci. 2023 Jan 16;24(2):1748. doi: 10.3390/ijms24021748. PMID: 36675263;PMCID: PMC9865211.
14: Wang M, Liu H, Ren J, Huang Y, Deng Y, Liu Y, Chen Z, Chow FW, Leung PH, LiS. Enzyme-Assisted Nucleic Acid Amplification in Molecular Diagnosis: A Review.Biosensors (Basel). 2023 Jan 19;13(2):160. doi: 10.3390/bios13020160. PMID:36831926; PMCID: PMC9953907.
15: Kwok CT, Chow FW, Cheung KY, Zhang XY, Mok DK, Kwan YW, Chan GH, Leung GP,Cheung KW, Lee SM, Wang N, Li JJ, Seto SW. Medulla Tetrapanacis water extractalleviates inflammation and infection by regulating macrophage polarizationthrough MAPK signaling pathway. Inflammopharmacology. 2024 Feb;32(1):393-404.doi: 10.1007/s10787-023-01266-1. Epub 2023 Jul 10. PMID: 37429999.
16: Chow FW, Morphew RM. Extracellular Vesicles in Microbes, Pathogens, andInfectious Diseases. Int J Mol Sci. 2023 Jun 26;24(13):10686. doi:10.3390/ijms241310686. PMID: 37445865; PMCID: PMC10341509.
One Health
1: Hau PT, Shiu A, Tam EW, Chau EC, Murillo M, Humer E, Po WW, Yu RC, Fung J,Seto SW, Tsang CC, Chow FW. Diversity and Antifungal Susceptibilities of Yeasts from Mangroves in Hong Kong, China-A One Health Aspect. J Fungi (Basel). 2024Oct 20;10(10):728. doi: 10.3390/jof10100728. PMID: 39452680; PMCID: PMC11508678.
2: Chow N, Long T, Lee LK, Wong IT, Lee AW, Tam WY, Wong HF, Leung JS, Chow FW,Luk KS, Ho AY, Lam JY, Yau MC, Que TL, Yip KT, Chow VC, Wong RC, Mok BW, ChenHL, Siu GK. Transmission Patterns of Co-Circulation of Omicron Sub-Lineages inHong Kong SAR, China, a City with Rigorous Social Distancing Measures, in 2022.Viruses. 2024 Jun 18;16(6):981. doi: 10.3390/v16060981. PMID: 38932272; PMCID:PMC11209396.
3: Wu WG, Shum MH, Wong IT, Lu KK, Lee LK, Leung JS, Lao HY, Lee AW, Hau PT,Chan CT, Wong HF, Fung SK, Wong SC, Ng IC, Ng TT, Chow N, Ho AY, Hung MF, ChowFW, Wong MM, To WK, Lam TT, Luk KS, Siu GK. Probable airborne transmission of Burkholderia pseudomalleicausing an urban outbreak of melioidosis duringtyphoon season in Hong Kong, China. Emerg Microbes Infect. 2023Dec;12(1):2204155. doi: 10.1080/22221751.2023.2204155. PMID: 37070526; PMCID:PMC10155638.